For the past few years we have been interested in the
synthesis, characterization and bioactivity of a series of compounds containing
both a trisubstituted tin functional group and a dithiocarbamate functional
group. The compounds we are making
have carbon spacers separating the tin and sulfur groups:
R = Me, Bu, Ph
n = 4, 6
We have also used a cyclohexane ring as a spacer.
The synthetic chemistry has led us to a study of the conformational
equilibria of cis- and trans- 1, 4-bromochlorocylohexane.
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